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ABCG2 had been shown to pump the dye out of cells, so we knew it must be highly active in these cells and hypothesized that it might also pump the carcinogenic compounds from cigarette smoke out of the cells. To test this hypothesis, the research team inhibited the activity of ABCG2 in the cancer cells in two ways and tested how the cells then reacted to cigarette smoke exposure

This technique, so specific to Van Gogh's work, appears in the famous paintings representing his bedroom (1888) and the Starry Night (1889)

Group III (SIL100-treated group), each mice was treated with 100 mg/kg bwt/day of SIL dissolved in 0.9% saline water via the i.p